Advantame is a new ultrahigh potency sweetener and flavor enhancer developed by Ajinomoto. It is derived from aspartame and vanillin. Advantame is approximately 20,000 times sweeter than sugar and 100 times sweeter than aspartame. It has zero calories and a clean, sweet, sugar-like taste with no undesirable taste characteristics. Suitable for most low- and non-calorie product formulations, it can be used in cooking and baking. Advantame gives food and drink manufacturers a new sweetening alternative to meet consumer demand for more low-calorie foods and beverages.


The results of numerous safety studies in animals and humans confirm that advantame is safe for use by the general population, including people with diabetes. Additionally, no special labeling is expected to be required.

Regulatory Status

Advantame has been approved for use in Australia and New Zealand. It had been deemed Generally Recognized As Safe (GRAS) as a flavor for use in non-alcoholic beverages, chewing gum, milk products and frozen dairy products. A Food Additive Petition was submitted in April 2009 to the US FDA seeking approval for use of advantame as a sweetener in powdered beverages and for tabletop use and it is under review by the European Food Safety Authority (EFSA).


Substantial scientific evidence supports advantame’s safe use by the millions of consumers who seek to control their intake of carbohydrate-based sweeteners and calories. Because advantame is much sweeter than most low and no-calorie sweeteners currently available, it is expected to be a top candidate for food and beverage formulations to meet the consumer demand for great tasting foods and beverages without the calories of sugar.

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